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Universal versus conditional three-day follow-up visit for children with unclassified fever at the community level

The current guidelines for the integrated community case management (iCCM) of childhood illness by community health workers (CHWs) call for treatment at the community level of febrile children without danger signs who have diarrhea, pneumonia, or malaria, and referral of any child with danger signs. Recent research suggests that in cases of febrile illness among children without danger signs, and with no other obvious cause of fever, expectant management at home can be safely used without a systematic reassessment visit to the CHW at three days.  The purpose of this Request for Applications (RFA) is to fund research that will assess the safety of CHW-advised expectant management at home of non-severe febrile illness in children aged 2 months to 5 years, in which no source of fever can be identified (i.e., malaria RDT-negative, no diarrhea, no cough/fast breathing, no rash or skin problems). Results of this research will be broadly shared to inform potential modification of current iCCM guidelines.

The priority countries for this research are Ethiopia, DRC, Senegal, Madagascar, Malawi, Zambia, and Rwanda. Other PMI-supported countries could be considered if they can demonstrate that an existing Integrated Community Case Management (iCCM) program, which includes Malaria RDT testing, of sufficient scale is already in place, and the rationale for conducting the research in the proposed country is clearly described. For a list of PMI-supported countries, please visit: http://www.pmi.gov/where-we-work.

A full list of questions received from interested parties by December 22, 2021 can be downloaded below.

Category: 
Previously Awarded
Date Awarded: 
Wednesday, April 15, 2022
Awarded to: 

International Rescue Committee, Inc. (IRC)

Malaria Consortium UK

File Attachment(s): 
AttachmentSize
icon for TRAction Fever RFA M2014-001.pdf Download the RFA995.52 KB
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